Stroh Lab - Publications

2024

April

Bioinformatics

ViNe-Seg: Deep-Learning assisted segmentation of visible neurons and subsequent analysis embedded in a graphical user interface.

Ruffini N, Altahini S, Weißbach S, Weber N, Milkovits J, Wierczeiko A, Backhaus H, Stroh A

DOI: 10.1093/bioinformatics/btae177 | PMID: 38569889.

March

Trends in Neurosciences

The selfish network: how the brain preserves behavioral function through shifts in neuronal network state.

Stroh A, Schweiger S, Ramirez JM, Tüscher O

DOI: 10.1016/j.tins.2024.02.005 | PMID: 38485625.

2023

August

Biological Chemistry

Optogenetics 2.0: challenges and solutions towards a quantitative probing of neural circuits.

Altahini S, Arnoux I, Stroh A

DOI: 10.1515/hsz-2023-0194 | PMID: 37650383.

February

Neuromethods Volume 191, Springer Nature

An All-Optical Physiology Pipeline Toward Highly Specific and Artifact-Free Circuit Mapping.

Backhaus H, Ruffini N, Wierczeiko A, Stroh A

DOI: 10.1007/978-1-0716-2764-8_5 | ISBN: 978-1-0716-2764-8

2022

November

International Journal of Molecular Sciences

Behavioral Phenotyping of Bbs6 and Bbs8 Knockout Mice Reveals Major Alterations in Communication and Anxiety.

Rödig N, Sellmann K, dos Santos Guilherme M, Nguyen V, Cleppien D, Stroh A, May-Simera H, Endres K.

DOI: 10.3390/ijms232314506 | PMID: 36498834.

November

Scientific Reports

Effects of optogenetic inhibition of a small fraction of parvalbumin-positive interneurons on the representation of sensory stimuli in mouse barrel cortex.

F. Yeganeh, B. Knauer, R. Guimarães Backhaus, J.-W. Yang, A. Stroh, H. J. Luhmann, M. Stüttgen.

DOI: 10.1038/s41598-022-24156-y | PMID: 36371511.

August

Journal of Neurophysiology

Functional States Shape the Spatiotemporal Representation of Local and Cortex-wide Neural Activity in Mouse Sensory Cortex.

Schwalm M, Tabuena DR, Easton C, Richner TJ, Mourad P, Watari H, Moody WJ, Stroh A.

DOI: 10.1152/jn.00424.2021 | PMID: 35975935.

July

Neurophotonics

Beyond correlation: functional OPTO-MAgnetic Integration Concept (OPTOMAIC) to reveal the brain-wide signature of local neuronal signals-of-interest.

Cleppien D, Aedo-Jury F, Stroh A.

DOI: 10.1117/1.nph.9.3.032213 | PMID: 35813935.

May

Journal of Imaging

Low-Cost Probabilistic 3D Denoising with Applications for Ultra-Low-Radiation Computed Tomography.

Horenko I, Pospíšil L, Vecchi E, Albrecht S, Gerber A, Rehbock B, Stroh A, Gerber S.

DOI: 10.3390/jimaging8060156 | PMID: 35735955.

April

Brain Stimulation

Non-ablative doses of focal ionizing radiation alters function of central neural circuits.

Zaer H, Fan W, Orlowski D, Glud AN, Jensen MB, Worm ES, Lukacova S, Mikkelsen TW, Fitting LM, Jacobsen LM, Portmann T, Hsieh JY, Noel C, Weidlich G, Chung W, Riley P, Jenkins C, Adler JR Jr, Schneider MB, Sørensen JCH, Stroh A.

DOI: 10.1016/j.brs.2022.04.001 | PMID: 35395424.

January

Cerebral Cortex

Individual Slow Wave Events Give Rise to Macroscopic fMRI Signatures and Drive the Strength of the BOLD Signal in Human Resting-State EEG-fMRI Recordings.

Ilhan-Bayrakcı M, Cabral-Calderin Y, Bergmann TO, Tüscher O, Stroh A.

DOI: 10.1093/cercor/bhab516 | PMID: 35094045.

2021

December

STAR Protocols

Pipeline for 2-photon all-optical physiology in mouse: From viral titration and optical window implantation to binarization of calcium transients.

Guimarães Backhaus R, Fu T, Backhaus H, Stroh A

DOI: 10.1016/j.xpro.2021.101010 | PMID: 35079708.

August

PNAS

Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation.

Larochelle C, Wasser B, Jamann H, Löffel JT, Cui QL, Tastet O, Schillner M, Luchtman D, Birkenstock J, Stroh A, Antel J, Bittner S, Zipp F

DOI: 10.1073/pnas.2025813118 | PMID: 34417310

March

Scientific Reports

Acitretin reverses early functional network degradation in a mouse model of familial Alzheimer’s disease.

Rosales Jubal E, Schwalm M, Dos Santos Guilherme M, Schuck F, Reinhardt S, Tose A, Barger Z, Roesler MK, Ruffini N, Wierczeiko A, Schmeisser MJ, Schmitt U, Endres K, Stroh A.

DOI: 10.1038/s41598-021-85912-0 | PMID: 33758244

February

iScience

Exploring two-photon optogenetics beyond 1100 nm for specific and effective all-optical physiology.

Fu T, Arnoux I, Döring J, Backhaus H, Watari H, Stasevicius I, Fan W, Stroh A.

DOI: 10.1016/j.isci.2021.102184 | PMID: 33718836

February

Frontiers in Human Neuroscience

An Intracortical Implantable Brain-Computer Interface for Telemetric Real-Time Recording and Manipulation of Neuronal Circuits for Closed-Loop Intervention.

Zaer H, Deshmukh A, Orlowski D, Fan W, Prouvot PH, Glud AN, Jensen MB, Worm ES, Lukacova S, Mikkelsen TW, Fitting LM, Adler JR, Schneider MB, Jensen MS, Fu Q, Go V, Morizio J, Sørensen JCH, Stroh A.

DOI: 10.3389/fnhum.2021.618626 | PMID: 33613212

2020

November

Frontiers in Human Neuroscience

A Perspective of International Collaboration Through Web-Based Telecommunication-Inspired by COVID-19 Crisis.

Zaer H, Fan W, Orlowski D, Glud AN, Andersen ASM, Schneider MB, Adler JR, Stroh A, Sørensen JCH.

DOI: 10.3389/fnhum.2020.577465 | PMID: 33328931

October

Statistics

A multi scale approach for testing and detecting peaks in time series.

Messer, M, Backhaus, H, Fu, T, Stroh, A., Schneider, G.

DOI: 10.1080/02331888.2020.1823980

October

Frontiers in Neuroscience

A Safe and Effective Magnetic Labeling Protocol for MRI-Based Tracking of Human Adult Neural Stem Cells.

Stroh A, Kressel J, Coras R, Dreyer AY, Fröhlich W, Förschler A, Lobsien D, Blümcke I, Zoubaa S, Schlegel J, Zimmer C, Boltze J.

DOI: 10.3389/fnins.2019.01092 | PMID: 31680827

July

Journal of Neuroscience

Increased Neural Activity in Mesostriatal Regions after Prefrontal Transcranial Direct Current Stimulation and l-DOPA Administration.

Meyer B, Mann C, Götz M, Gerlicher A, Saase V, Yuen KSL, Aedo-Jury F, Gonzalez-Escamilla G, Stroh A, Kalisch R.

DOI: 10.1523/jneurosci.3128-18.2019 | PMID: 31043485

June

Elife

Brain states govern the spatio-temporal dynamics of resting-state functional connectivity.

Aedo-Jury F, Schwalm M, Hamzehpour L, Stroh A.

DOI: 10.7554/elife.53186 | PMID: 32568067

March

Journal of Experimental Medicine

CNS-localized myeloid cells capture living invading T cells during neuroinflammation.

Wasser B, Luchtman D, Löffel J, Robohm K, Birkner K, Stroh A, Vogelaar CF, Zipp F, Bittner S.

DOI: 10.1084/jem.20190812 | PMID: 32219436

March

PLOS Biology

Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo.

Kur IM, Prouvot PH, Fu T, Fan W, Müller-Braun F, Das A, Das S, Deller T, Roeper J, Stroh A, Momma S.

DOI: 10.1371/journal.pbio.3000643 | PMID: 32176686

January

The Journal of Clinical Investigation

β1-Integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells.

Birkner K, Wasser B, Ruck T, Thalman C, Luchtman D, Pape K, Schmaul S, Bitar L, Krämer-Albers EM, Stroh A, Meuth SG, Zipp F, Bittner S.

DOI: 10.1172/jci126381 | PMID: 31661467

2018

September

Scientific Reports

Excitability regulation in the dorsomedial prefrontal cortex during sustained instructed fear responses: a TMS-EEG study.

Gonzalez-Escamilla G, Chirumamilla VC, Meyer B, Bonertz T, von Grotthus S, Vogt J, Stroh A, Horstmann JP, Tüscher O, Kalisch R, Muthuraman M, Groppa S.

DOI: 10.1038/s41598-018-32781-9 | PMID: 30267020

September

Nature Neuroscience

Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis.

Ellwardt E, Pramanik G, Luchtman D, Novkovic T, Jubal ER, Vogt J, Arnoux I, Vogelaar CF, Mandal S, Schmalz M, Barger Z, Ruiz de Azua I, Kuhlmann T, Lutz B, Mittmann T, Bittner S, Zipp F, Stroh A.

DOI: 10.1038/s41593-018-0193-2 | PMID: 30258239

September

Elife

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.

Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A.

DOI: 10.7554/elife.38744 | PMID: 30179155

2017

October

Neuromethods Volume 133, Springer Nature

Optogenetics: A Roadmap

Editors: Albrecht Stroh

DOI: 10.1007/978-1-4939-7417-7 | ISBN: 978-1-4939-7415-3

October

Cerebral Cortex

Optogenetic Modulation of a Minor Fraction of Parvalbumin-Positive Interneurons Specifically Affects Spatiotemporal Dynamics of Spontaneous and Sensory-Evoked Activity in Mouse Somatosensory Cortex in Vivo.

Yang JW, Prouvot PH, Reyes-Puerta V, Stüttgen MC, Stroh A, Luhmann HJ.

DOI: 10.1093/cercor/bhx261 | PMID: 29040472

September

Elife

Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves.

Schwalm M, Schmid F, Wachsmuth L, Backhaus H, Kronfeld A, Aedo Jury F, Prouvot PH, Fois C, Albers F, van Alst T, Faber C, Stroh A.

DOI: 10.7554/elife.27602 | PMID: 28914607

February

Stem Cell Reports

Astrocytic Calcium Waves Signal Brain Injury to Neural Stem and Progenitor Cells.

Kraft A, Jubal ER, von Laer R, Döring C, Rocha A, Grebbin M, Zenke M, Kettenmann H, Stroh A, Momma S.

DOI: 10.1016/j.stemcr.2017.01.009 | PMID: 28216142

2016

September

Neuron

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.

Cheng J, Sahani S, Hausrat TJ, Yang JW, Ji H, Schmarowski N, Endle H, Liu X, Li Y, Böttche R, Radyushkin K, Maric HM, Hoerder-Suabedissen A, Molnár Z, Prouvot PH, Trimbuch T, Ninnemann O, Huai J, Fan W, Visentin B, Sabbadini R, Strømgaard K, Stroh A, Luhmann HJ, Kneussel M, Nitsch R, Vogt J.

DOI: 10.1016/j.neuron.2016.08.035 | PMID: 27641493

July

Journal of Cerebral Blood Flow & Metabolism

Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings.

Schmid F, Wachsmuth L, Schwalm M, Prouvot PH, Jubal ER, Fois C, Pramanik G, Zimmer C, Faber C, Stroh A.

DOI: 10.1177/0271678x15619428 | PMID: 26661247

January

Magnetic Resonance in Medicine

True and apparent optogenetic BOLD fMRI signals.

Schmid F, Wachsmuth L, Albers F, Schwalm M, Stroh A, Faber C.

DOI: 10.1002/mrm.26095 | PMID: 26778283

January

EMBO Molecular Medicine

Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP.

Vogt J, Yang JW, Mobascher A, Cheng J, Li Y, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, Horta G, Radyushkin K, Stroh A, Richers S, Sahragard N, Distler U, Tenzer S, Qiao L, Lieb K, Tüscher O, Binder H, Ferreiros N, Tegeder I, Morris AJ, Gropa S, Nürnberg P, Toliat MR, Winterer G, Luhmann HJ, Huai J, Nitsch R.

DOI: 10.15252/emmm.201505677 | PMID: 26671989

2014

January

Methods in Molecular Biology

A roadmap to applying optogenetics in neuroscience.

Fois C, Prouvot PH, Stroh A.

DOI: 10.1007/978-1-4939-0470-9_9 | PMID: 24718799

2013

July

Cereb Cortex

Convergence of Cortical and Sensory Driver Inputs on Single Thalamocortical Cells.

Groh A, Bokor H, Mease RA, Plattner VM, Hangya B, Stroh A, Deschenes M, Acsády L.

DOI: 10.1093/cercor/bht173 | PMID: 23825316

May

PLOS One

Imaging of VSOP labeled stem cells in agarose phantoms with susceptibility weighted and T2* weighted MR Imaging at 3T: determination of the detection limit.

Lobsien D, Dreyer AY, Stroh A, Boltze J, Hoffmann KT.

DOI: 10.1371/journal.pone.0062644 | PMID: 23667503

March

Neuron

Making waves: initiation and propagation of corticothalamic Ca2+ waves in vivo.

Stroh A, Adelsberger H, Groh A, Rühlmann C, Fischer S, Schierloh A, Deisseroth K, Konnerth A.

DOI: 10.1016/j.neuron.2013.01.031 | PMID: 23522048

2012

September

Cytotherapy

Intrahippocampal transplantation of mesenchymal stromal cells promotes neuroplasticity.

Coquery N, Blesch A, Stroh A, Fernández-Klett F, Klein J, Winter C, Priller J.

DOI: 10.3109/14653249.2012.694418 | PMID: 22762522

2011

December

Journal of Physiology

Sound-evoked network calcium transients in mouse auditory cortex in vivo.

Grienberger C, Adelsberger H, Stroh A, Milos RI, Garaschuk O, Schierloh A, Nelken I, Konnerth A.

DOI: 10.1113/jphysiol.2011.222513 | PMID: 22106174

January

Stem Cells

Tracking stem cell differentiation in the setting of automated optogenetic stimulation.

Stroh A, Tsai HC, Wang LP, Zhang F, Kressel J, Aravanis A, Santhanam N, Deisseroth K, Konnerth A, Schneider MB.

DOI: 10.1002/stem.558 | PMID: 21280159

2009

May

Molecular Imaging

Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of Parkinson disease.

Stroh A, Boltze J, Sieland K, Hild K, Gutzeit C, Jung T, Kressel J, Hau S, Reich D, Grune T, Zimmer C.

DOI: 10.2310/7290.2009.00017 | PMID: 19723474

2006

September

NeuroImage

Tracking of systemically administered mononuclear cells in the ischemic brain by high-field magnetic resonance imaging.

Stroh A, Zimmer C, Werner N, Gertz K, Weir K, Kronenberg G, Steinbrink J, Mueller S, Sieland K, Dirnagl U, Nickenig G, Endres M.

DOI: 10.1016/j.neuroimage.2006.07.009 | PMID: 16973381

March

World Journal of Gastroenterology

Cerebral processing of auditory stimuli in patients with irritable bowel syndrome.

Andresen V, Poellinger A, Tsrouya C, Bach D, Stroh A, Foerschler A, Georgiewa P, Schmidtmann M, van der Voort IR, Kobelt P, Zimmer C, Wiedenmann B, Klapp BF, Monnikes H.

DOI: 10.3748/wjg.v12.i11.1723 | PMID: 16586541